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Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity Garvey WT, et al

People who were overweight or obese lost significant weight while taking retatrutide, which enabled them to be more active and reduced knee pain by an average of 4.5 points or about 76% based on pain scores from whats known as the Western Ontario and McMaster Universities Osteoarthritis Index

Since SPRMs affect basic cell programming in hormone-sensitive tissues (not just the uterus) and are known to change endometrial architecture in novel ways, are they associated with an increased risk for cancer SPRMs are now being administered in Europe, so well be paying close attention to outcomes there

Cancer Cell 10 , 257268 (2006)