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The starting dose for severe deficiency is typically 1500mcg (the full dose of the 1ml vial) given daily or on alternate days for 1 to 2 weeks, or until haematological remission is achieved

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Chloramphenicol and other drugs having bone marrow suppressant properties may cause a lack of therapeutic response to vitamin B12

Learn More Research review and sources Primary references and supporting sources Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction Recent preclinical 5A1MQ paper describing obesity, glucose, and liver endpoints