The committee also concluded, however, that e-cigarettes do have biological effects in humans, and the available evidence suggests that their long-term use likely increases risk of disease
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In 1971, the company introduced Mini Cigarillos, made entirely from tobacco short fillers
Other studies in adults have also shown that smoking has a negative impact on the postoperative outcome of nasosinusal endoscopic surgery when assessed under the viewpoint of symptoms, quality of life scores, endoscopic analysis and CT-scan findings.32,33,34 In the pediatric population, Kim et al.35, retrospectively assessed 97 patients submitted to paranasal sinuses surgery, and showed that children exposed to cigarette smoke had a worse postoperative outcome based on endoscopic analysis
