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The results demonstrated that the 6-week chronic MitoQ administration effectively improved the circulatory microenvironment, enhanced endothelial function, and alleviated mitochondrial oxidative stress by downregulating oxLDLLOX1 signaling, providing direct experimental evidence supporting the beneficial effects of MitoQ on vascular endothelial function in the elderly population

Comparison with other antioxidant therapies Both efficacy and safety profiles are critical when comparing silymarin to vitamin E and other antioxidants

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though interventions are in early stages, they represent a promising future direction