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Cancer Invest

doi: 10.1007/BF02523627 4 MortonDLThompsonJFCochranAJMozzilloNElashoffREssnerRet al

Thus, future progress will require integrated studies based on human pancreatic tissue, spatial and single-cell transcriptomics, organelle-oriented proteomics, advanced imaging, and correlative ultrastructural analysis in well-characterized patient cohorts in order to determine to what extent the mitochondrial hub model established in experimental systems is conserved in human disease