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In some cases, it may be difficult to differentiate pain from AC joint pathology from other shoulder pathology, particularly rotator cuff impingement syndrome

Antioxidants play a pivotal role in neutralizing ROS and preventing oxidative damage to melanocytes, which is crucial for maintaining skin pigmentation and reducing the risk of disorders like vitiligo or melanoma (Table 2)

Further research investigating time-course changes in citrulline concentration following CM supplementation is required to determine the optimal strategy, although the best recommendation at the moment would be 1 h prior to exercise

Biological repair and adaptation rarely depend on a single signaling molecule, and many modern studies increasingly focus on network-level interactions rather than isolated mechanisms