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10.1016/j.expneurol.2011.10.021 Exp

Further reported systemic complications include renal infarction and rhabdomyolysis

Drug treatment and hypoxia Unless otherwise stated, cells were treated with a concentration of 50 M (-)-Lobeline hydrochloride (Tocris Bioscience, 134-63-4)

The compounds quinolinium scaffold mimics nicotinamides structure, allowing it to compete for the NNMT active site while avoiding interactions with other enzymes