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Numbers of -SMA positive blood vessels were the highest in the conventional cigarette group (Table I)

That said, those using nicotine patch instead of continued smoking or vaping will decrease their exposure to nicotine, which is why, under careful supervision by a tobacco treatment provider, NRT can still be used in these populations

People using a patch never get a big spike of nicotine like when smoking, which delivers nicotine to the brain in 7 seconds and leads to multiple larger spikes of nicotine absorption throughout the day