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This effect is potentially mediated through the activation of the Nrf2 pathway, which plays a pivotal role in mitigating oxidative stressa major factor in dopaminergic neuron degeneration (Ko and Attenberger, 2024)

NEMO-binding domain peptide (NBD) The inhibitor of nuclear factor kappa-B kinase (IKK) is a high molecular weight complex consisting of two catalytic subunits (IKK-1 and IKK-2) and a non-catalytic regulatory subunit NF-kB Essential Modulator (NEMO or IKK-) [194]