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Gegen Qinlian Decoction with 5-ASA increases clinical response rates by approximately 22%, while Xilei San improves mucosal healing by about 25% ( 3 Challenges and prospects in clinical translation Although combination therapy with 5-ASA and natural active ingredients from TCM has demonstrated promising synergistic effects and therapeutic potential in both basic and preclinical studies of UC, its translation into large-scale clinical applications still faces multiple challenges

The absence of muscle-building effects means weight changes reflect primarily fat loss rather than mixed body recomposition

HERO INGREDIENTS

The authors are grateful to Douglas Strand from UTSW Department of Urology for his assistance with RNAscope experiments and Lauren Zacharias from the CRI Metabolomics Facility for her assistance with metabolomic analyses