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According to the World Health Organization (WHO), glutathione plays a critical role in reducing oxidative stress and supporting cellular health

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The prescribing information notes that gastrointestinal adverse effects are the most common reasons for treatment discontinuation

At this point, we have previously shown that IGF-I is a main character in restoring mitochondrial dysfunction during aging by increasing mitochondrial membrane potential, reducing oxygen consumption, and increasing ATP synthesis what in turn minimize the c-cytochrome release to the cytoplasm and subsequently promote neural survival by decreasing caspase-induced apoptosis[55, 56], in agreement with in vitro reported works from others[242244]