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The mechanistic comparison is particularly interesting: CagriSema adds amylin signaling to GLP-1, while retatrutide adds glucagon and GIP signaling

Astrocyte scar formation aids central nervous system axon regeneration

NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway

While this is only a recommendation and not a final FDA decision, it's an encouraging step that could help expand future access to peptide therapy in the United States