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Para los adultos mayores que lidian con mayor susceptibilidad a infecciones y menor respuesta a vacunas manifestaciones de la inmunosenescencia esta dimensin restauradora del sistema inmune es clnicamente relevante

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In mice infected with MRSA, which is an important and dangerous human pathogen, treatment with spermidine reduced the MRSA burden in the bloodstream and limited systemic inflammation by polarising macrophages toward the anti-inflammatory M2 phenotype