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Conditions like pernicious anaemia (an autoimmune disorder where your body cant absorb B12 from food), certain stomach conditions, medications that reduce stomach acid, or even gastrointestinal surgeries (like weight loss surgery) can prevent your body from properly taking in B12, even if youre getting enough in your diet

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The heterogeneity of zones allows cells to perform specific functions effectively in response to various injuries

135,136,137 SIRT3 also enhances cellular antioxidant capacity through augmenting the reducing power, NADPH, and increasing the activity of antioxidant enzymes, such as SOD2 and catalase