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This extended urinary detection suggests continued metabolism of tissue-bound peptide or slow release from tissue reservoirs

The coils are delivered via a catheter, which is inserted through the jugular vein into the shunt under fluoroscopic guidance in anesthetized animals.114, 115 The coils cause thrombus formation in the shunt resulting in its partial or complete occlusion

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These ROS have high reactivity with other biological molecules, inducing oxidative stress and directly damage cellular membranes via lipid peroxidation [61]