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At Week 26, treatment with a 2 mg dose of EGRIFTA (1 mg/vial formulation) resulted in a reduction from baseline in mean trunk fat of 1.0 kg in Study 1 and 0.8 kg in Study 2, respectively (compared with an increase of 0.4 kg in Study 1 and of 0.2 kg in Study 2, respectively, in patients receiving placebo)

Those are covered at the end of this article

Most people find this to be uncomfortable, but not unbearable, and it dramatically impacts the results you get - so its a tradeoff most people are willing to make

Honestly, I think this actually works and especially after children and after menopausal changes - from experience of patients who have had it, they really rate it