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The peptide appears to influence slow-wave sleep (SWS) promotion while simultaneously modulating hypothalamic-pituitary-adrenal (HPA) axis activity and reducing stress hormone levels

4.3 Modulation of chemokine dysregulation Chemokines are small, secreted proteins produced by both structural and immune cells that regulate immune responses at sites of inflammation by directing immune cell migration through interactions with G protein-coupled receptors, including CC chemokine receptors (CCR) and CXC chemokine receptors (CXCR) (Liu J

In agreement with in vitro findings, DMF treatment induced the expression of Cbs, Ahcy, and NRF2 targets such as Gclc, Gclm, and Slc7a11, but not that of Cse (Fig

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