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VD alone did not show effect on GSH, TNF-, VDBP , IR, and HbA 1c

Perimenopause can disrupt sleep through night sweats, anxiety, and hormonal shifts that affect cortisol (stress hormone) rhythms and blood sugar regulation

However, a breakthrough came with the observation that TICs, rather than the bulk of differentiated tumor cells, thrive in 3D gels [23, 24], offering an opportunity to uncover signaling pathways specific to TIC growth and identify TIC-specific therapeutic targets