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Animals and procedures The animal experimental procedures were approved by the Animal Care and Use Committee of Oujiang Laboratory (SYXK2023-0047, OJLAB22121609), and were carried out in strict accordance with the National Institutes of Health Guidelines for the Use of Laboratory Animals

While these supplements and over-the-counter medications contain some peptides, they are largely ineffective because they do not contain enough peptides to make a noticeable difference

Research Highlights Current research demonstrates: Significant reductions in pain scores Improved mobility and walking comfort Low complication rates Strong potential as a long-term alternative to surgery As clinical studies continue, PFE is gaining recognition nationwide as one of the most effective non-surgical options for chronic heel pain