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Xu X, Stambrook PJ

This comprehensive narrative Review underscores the diverse health benefits of Ashwagandha, emphasizing its roles in immunomodulation, stress reduction, antioxidant effects, cardioprotection, anti-inflammatory, anti-tumor, and anti-cancer activities, neuroprotection, memory enhancement, cognitive function, physical performance, and sexual health improvement effects

Neutralizes harmful free radicals

Additionally, proteolysis targeting chimeras (PROTACs) offer a novel approach to modulate ferroptosis: PROTACs targeting ACSL4 or Nrf2 have been developed to either induce ferroptosis (in renal cell carcinoma) or enhance antioxidant defense (in CKD), respectively, with improved specificity compared to small-molecule inhibitors