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9 Conclusion and prospects NP-based cancer treatment has emerged as a revolutionary approach in precision oncology, addressing a range of issues related to drug release profiles, target selectivity, and control of cellular signaling pathways linked to cancer

However, the approach carries risks

Patients should be counselled regarding the risk of weight gain

Instead, the selected literature was analyzed and synthesized thematically, with studies grouped according to biological pathways (e.g., monoaminergic modulation, neurotrophic signaling, HPA-axis regulation, neuroinflammation, oxidative stress, and mitochondrial function) and level of evidence (preclinical versus clinical)