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In the pilot, Smoke Gets in Their Eyes, Don has to think of a clever way to sell Lucky Strikes after the 1960 Readers Digest report linking cigarettes and cancer

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As such, it's banned on cruise ships since terminals are federal facilities

Food and Drug Administration (FDA) Vaporizers, E-Cigarettes, and other Electronic Nicotine Delivery Systems (ENDS) Centers for Disease Control and Prevention (CDC) Flavorings-Related Lung Disease Link to CDC Occupational Safety and Health Administration (OSHA) Diacetyl and Food Flavorings National Institute for Occupational Safety and Health (NIOSH) Preventing Lung Disease in Workers Who Use or Make Flavorings Link to NIOSH American Lung Association Popcorn Lung: A Dangerous Risk of Flavored E-Cigarettes