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A limitation of the study is the necessity for in vitro and further in vivo studies to investigate additional protective mechanistic pathways of MCP against MTX-induced hepatic and pulmonary toxicity

A screening guide was developed prior to the initial screening to train all reviewers on the eligibility criteria (protocol CRD420251088025 in PROSPERO)

Zn-Regulated GTPase Metalloprotein Activator 1 Modulates Vertebrate Zinc Homeostasis

Ferroptosis sensitivity is closely linked to various biological processes, including amino acid metabolism, iron metabolism, PUFA metabolism, GSH synthesis, and phospholipid (PL) synthesis