AOD-9604, by contrast, acts directly on adipose (fat) cells without touching the GH axis, and does not raise IGF-1
Furthermore, since AOD 9604 therapy does not significantly impact growth and only slightly affects hormone pathways, it is safe to use on a long-term basis with continued medical supervision
Headquartered in Tel Aviv, Teva is the world's largest generic pharmaceutical company and a significant specialty innovator, with a particular position in the peptide therapy market through Copaxone (glatiramer acetate) a synthetic peptide copolymer that has been the world's best-selling multiple sclerosis treatment for two decades and AJOVY (fremanezumab), a CGRP-targeting monoclonal antibody for migraine prevention that occupies the neurological peptide signalling space
Studies have explored its effects on collagen synthesis, angiogenesis, antioxidant pathways, and modulation of signalling relevant to tissue remodelling