Notably, strong red fluorescence was observed in RAW264.7 cells incubated with Mn/TI@mHSA, while the control Mn/TI@HSA showed reduced binding to RAW cells (Fig
T.ItoK.TanakaK.KojimaH.KidoH
In fact, it has been suggested that reduced exposure to free radicals and increased intake of antioxidant rich foods or antioxidant supplements will enhance the bodys potential to minimize the risk of free radical related health problems.3 Antioxidants such as polyphenols, ascorbic acid, vitamin A, alpha-lipoic acid, thioredoxin, glutathione, melatonin, coenzyme Q, beta carotenoids, alpha-tocopherols as well as antioxidant enzymes including superoxide dismutase, catalase, glutathione-peroxidases , glutathione reductases and glutathione-s-transferases have been widely investigated for the prevention and treatment of diseases resulting from oxidative damage.4, 5, 6, 7 2
In turn, this inhibition leads to suppression of the production of inflammatory cytokines such as IL-6, TNF and IL-8 as shown for various immune cells in vitro , in animal immune models and in immune-compromised human (129131)