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Myo-inositol (with or without D-chiro-inositol) If there's one supplement you've probably already heard about on your PCOS journey, it's myo-inositol and the research backs up a lot of the buzz

For example, encapsulating the adjuvant monophosphoryl lipid A in the core of poly(D, L-lactide-co-glycolide) nanoparticles and then modifying the surface with the tumor-targeting peptide TMTP1 and the DC receptor mannose to form the nanovaccine NP-TP1@MM can capture and enrich more tumor-specific antigens after chemotherapy, stimulate DCs maturation and activate adaptive immunity (103)

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This, in turn, limits the availability of SAMe for methylation 12