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Conversely, treatment with specific beneficial bacteria enhances their protective effects, such as producing SCFAs and lowering uremic toxins, leading to the suppression of NF-B and TGF-/Smad pathways, reducing oxidative stress, and activating the Nrf2 pathway

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An estimated 14,480 geriatricians will be needed to care for the approximately 10.1 million individuals age 65 and older who are projected to have Alzheimer's dementia in 2050