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GHK-Cu has the most extensive human safety data of the three, with years of use in cosmetic and wound-healing applications demonstrating a favorable safety profile

This sequence is crucial for the compound's biological activity

Subsequently, repair or degeneration occur, which depend on multiple factors such as the type and extent of damage, the immune system, the genetic susceptibility to disc degeneration, which is linked with age, the biomechanical (functional) condition that is created by the injury, and finally the type of treatment: conservative (disc loading) or operative (disc unloading)

[PubMed] 18.Leon Kircik