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Time to reconsider the mechanism

Anomalous levels of Cl transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory

The tripeptide backbone confers high-affinity copper chelation through coordination at the histidine imidazole nitrogen and the terminal amine, forming a stable square-planar complex that modulates the bioavailability and redox activity of Cu in experimental systems