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For patients with chronic dryness, sensitivity, or suspected barrier weakness, it can be a helpful part of the overall strategy

Unlike classic dietary antioxidants (vitamin C, vitamin E) which localize to specific compartments, melatonin being both lipophilic and hydrophilic distributes through all cellular compartments, especially concentrating in mitochondria where the majority of ROS are produced

But most of these drugs are not approved for human consumption by regulators, because we dont fully understand what theyre doing to our bodies