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(74) found that NOR had a pro-apoptotic effect on FLSs of AIA rats, and its molecular mechanism was achieved by promoting the release of cytochrome C, regulating the Bax/Bcl-2 expression-mediated mitochondrial dependent pathway, and up-regulating the p53 pathway

In addition, transforming growth factor-1 (TGF-1), a potent fibrogenic protein, is known to upregulate astrocyte synthesis of proteoglycans causing severe gliosis (Yin et al., 2009

In addition, storage conditions and cooking can decrease the amount of glutathione found in these plant foods

Glutathione, a Key Intracellular Antioxidant GSH is a tripeptide consisting of amino acids L-glutamate, L-cysteine, and L- glycine, having a molecular weight of 307.4 g mol 1