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94 As previously described, a controlled trial found 20 mg CoQ10 three times daily, when combined with 1 gram L-carnitine twice daily, resulted in a higher pregnancy rate than either supplement alone or placebo in 262 men with infertility and abnormal semen analyses

For instance, topical applications often require higher concentrations at the site of action compared to injected methods, which bypass first-pass metabolism

Its chemical stability in gastric environments and efficacy across multiple administration routes make it a candidate for further investigation in regenerative pharmacology 2