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Diet and exercise remain the foundation every other intervention is built on, and they meaningfully improve obesity-related conditions such as hypertension and type 2 diabetes

A higher rate of clinically significant hypoglycemic episodes was reported with the semaglutide 2.4 mg/week dose versus the 1 mg/week dose (10.7 vs

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all tests were two-tailed and = 0.05 for each analysis