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Here's how nicotine impacts the body: Impacts Blood Sugar Levels: Nicotine triggers stress hormones like cortisol and adrenaline, which raise blood glucose

That's when filtered cigarettes started becoming popular, and the new smokes solved several of the problems that cigarette holders did (per The New York Times)

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doi: 10.3389/fpsyt.2023.1134079 Received 29 December 2022 Accepted 31 July 2023 Published 14 August 2023 Volume 14 - 2023 Edited by Kristine C-Y McGrath, University of Technology Sydney, Australia Reviewed by Kabirullah Lutfy, Western University of Health Sciences, United States